20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12233 | NK-1 Antagonist 1 | Rolapitant intermediate | Others |
NK-1 Antagonist 1 is a NK-1 receptor antagonist. | |||
T6905 | Netupitant | Ro 67-31898/000,CID 6451149 | Neurokinin receptor |
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). | |||
T13306L | Vapreotide acetate | RC-160 acetate,BMY-41606 acetate | Neurokinin receptor |
Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM). | |||
T68068 | Ezlopitant | CJ 11974,CJ-11974,CJ11974 | Neurokinin receptor |
Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain. | |||
T3716 | Rolapitant | SCH619734 | Neurokinin receptor |
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... | |||
T3724 | Rolapitant hydrochloride | Rolapitant HCl | Neurokinin receptor |
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY... | |||
T28917 | TAK-637 | TAK 637 | |
TAK-637 is a tachykinin 1 (NK1) receptor antagonist. | |||
T9471 | Imnopitant | ||
Imnopitant is an antagonist of the NK1 receptor [1]. | |||
T13306 | Vapreotide | BMY 41606,RC160 | Others |
Vapreotide is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM). | |||
T10688 | Casopitant mesylate | GW679769B | P450 , Neurokinin receptor |
Casopitant mesylate (GW679769B) is a selective, brain permeable, and orally active antagonist of neurokinin 1 (NK1) receptor. It is a second in the class of antiemetics. | |||
T73705 | Imnopitant dihydrochloride | ||
Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist [1] . | |||
T78104 | Fosnetupitant chloride monohydrochloride | Pronetupitant chloride monohydrochloride | Neurokinin receptor |
Fosnetupitant chloride monohydrochloride (Pro-netupitant chloride monohydrochloride) is a selective NK1 antagonist exhibiting high affinity for the human NK1 receptor with a pK i value of 9.5, and a lower affinity for th... | |||
T38033 | Benzomalvin B | ||
Benzomalvin B is a fungal metabolite originally isolated from Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μ... | |||
T66676 | SCH619734 SCH-619734 | ||
Rolapitant Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. | |||
T71833 | Acetylaszonalenin | ||
Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes.1 It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P with a Ki value of 170 μM. | |||
T71935 | WIN 66306 | ||
WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated g... | |||
T80031 | [D-Pro2] Spantide I TFA | Neurokinin receptor | |
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1]. | |||
T70456 | Nolpitantium Free Base | ||
Nolpitantium Free Base is a highly selective nonpeptide antagonist of neurokinin-1 (NK1) receptor. Nolpitantium potently, selectively and competitively inhibited substance P binding to NK1 receptors from various animal s... | |||
T68371 | Rolapitant hydrochloride hydrate | ||
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant compe... | |||
T75837 | Spantide I TFA | ||
Spantide I TFA, a selective NK1 receptor antagonist and a substance P analog, exhibits K(i) values of 230 nM for NK1 and 8150 nM for NK2 receptors, respectively. It offers a method to decrease type 1 while increasing typ... |